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Our lab investigates the structure and function of cell surface membranes in human pathogens, and how these relate to disease, evolution and development of treatment. Through studies of cell surface composition and architecture of African trypanosomes, both at the level of molecular targets and of cellular organization, our work is making significant contributions to membrane specialisation that is critical for parasitism and to possible exploitation for therapeutic gain.
A uniting factor behind these topics is the importance they have to understanding the biology of parasites and the evolution of complex cells. Much of the work in the lab involves the parasite Trypanosoma brucei.
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I caught that tryps.rockefeller.edu is weilding the Apache/2.2.29 (Unix) DAV/2 mod_ssl/2.2.29 OpenSSL/0.9.8zd operating system.PAGE TITLE
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Serving the trypanosome research. The top left panel shows original drawings by Surgeon-Captain David Bruce, of the British Army Medical Service, who identified Trypanosoma brucei as the cause of the tsetse fly disease in African cattle in 1895. The human disease is called Sleeping Sickness. Infection leads rapidly to coma and death. The left panel shows a color-enhanced scanning electron micrograph of Trypanosoma brucei among blood cells. Michael Duszenko, University of Tübingen, Germany. Clear your c.CONTENT
This web page had the following on the site, "The top left panel shows original drawings by Surgeon-Captain David Bruce, of the British Army Medical Service, who identified Trypanosoma brucei as the cause of the tsetse fly disease in African cattle in 1895." We saw that the web page said " The human disease is called Sleeping Sickness." It also said " Infection leads rapidly to coma and death. The left panel shows a color-enhanced scanning electron micrograph of Trypanosoma brucei among blood cells. Michael Duszenko, University of Tübingen, Germany." The header had TRYPANOSOMIASIS as the highest ranking optimized keyword. It is followed by AFRICAN SLEEPING SICKNESS, NAGANA, and TSETSE which isn't as ranked as highly as TRYPANOSOMIASIS. The next words tryps.rockefeller.edu uses is GLOSSINA. CHAGAS DISEASE was included and could not be seen by web engines.VIEW SUBSEQUENT WEB PAGES
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